Gene
vcanb
- ID
- ZDB-GENE-030131-2185
- Name
- versican b
- Symbol
- vcanb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and hyaluronic acid binding activity. Involved in intramembranous ossification and skeletal system development. Predicted to localize to extracellular matrix. Human ortholog(s) of this gene implicated in intracranial aneurysm. Is expressed in several structures, including dermatocranium; dorsolateral septum; otic vesicle; paraxial mesoderm; and ventral fin fold. Orthologous to human VCAN (versican).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Wagner syndrome 1 | 143200 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Conserved_site | IPR018378 | C-type lectin, conserved site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR000538 | Link domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Domain | IPR033987 | Aggrecan/versican, C-type lectin-like domain |
| Family | IPR050691 | Hyaluronan-binding Proteoglycan |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Aggrecan/versican, C-type lectin-like domain | C-type lectin, conserved site | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Hyaluronan-binding Proteoglycan | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin V-set domain | Link domain | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q75ZI3
|
1570 |
Interactions and Pathways
No data available
Plasmids
No data available