Gene

metap2b

ID
ZDB-GENE-030131-2172
Name
methionyl aminopeptidase 2b
Symbol
metap2b Nomenclature History
Previous Names
  • metap2
  • wu:fb98h06
  • zgc:66250
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity and metalloaminopeptidase activity. Involved in Wnt signaling pathway; definitive hemopoiesis; and hematopoietic stem cell differentiation. Predicted to localize to cytoplasm. Is expressed in several structures, including digestive system; heart tube; hematopoietic system; pronephric duct; and trunk. Orthologous to human METAP2 (methionyl aminopeptidase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With metap2b Human Ortholog
No data available
Associated With metap2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site
Domain IPR000994 Peptidase M24
Family IPR001714 Peptidase M24, methionine aminopeptidase
Family IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2
Family IPR050247 Methionine Aminopeptidase Type 2
Homologous_superfamily IPR036005 Creatinase/aminopeptidase-like
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Creatinase/aminopeptidase-like Methionine Aminopeptidase Type 2 Peptidase M24 Peptidase M24A, methionine aminopeptidase, subfamily 2 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site Peptidase M24, methionine aminopeptidase Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q7SXK1 476
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA metap2b-201 (1) Ensembl 3,008 nt
ncRNA ottdart00000062074 (1) Ensembl 784 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations