Gene

atg7

ID
ZDB-GENE-030131-1633
Name
ATG7 autophagy related 7 homolog (S. cerevisiae)
Symbol
atg7 Nomenclature History
Previous Names
  • fb76g05
  • im:7158252
  • wu:fb76g05
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have ubiquitin-like modifier activating enzyme activity. Involved in autophagosome assembly; heart development; and mitophagy. Predicted to localize to cytoplasm. Is expressed in brain; liver; and muscle. Orthologous to human ATG7 (autophagy related 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atg7 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 31 Alliance Spinocerebellar ataxia, autosomal recessive 31 619422
Associated With atg7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000594 THIF-type NAD/FAD binding fold
Domain IPR032197 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal
Family IPR006285 Ubiquitin-like modifier-activating enzyme Atg7
Family IPR045886 ThiF/MoeB/HesA family
Homologous_superfamily IPR035985 Ubiquitin-activating enzyme
Homologous_superfamily IPR042522 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1
Homologous_superfamily IPR042523 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2
Domain Details Per Protein
Protein Length ThiF/MoeB/HesA family THIF-type NAD/FAD binding fold Ubiquitin-activating enzyme Ubiquitin-like modifier-activating enzyme Atg7 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2
UniProtKB:A0A8M9QHT7 704
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA atg7-201 (1) Ensembl 2,133 nt
mRNA atg7-202 (1) Ensembl 1,451 nt
mRNA atg7-203 (1) Ensembl 612 nt
mRNA atg7-204 (1) Ensembl 303 nt
mRNA atg7-205 (1) Ensembl 1,000 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations