Gene

ewsr1b

ID
ZDB-GENE-030131-1600
Name
EWS RNA-binding protein 1b
Symbol
ewsr1b Nomenclature History
Previous Names
  • fb40b11 (1)
  • fusl
  • wu:fb40b11 (1)
  • wu:fb75g09
  • zgc:55864
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and transcription coregulator activity. Involved in central nervous system neuron development and mitotic cell cycle. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Ewing sarcoma. Orthologous to human EWSR1 (EWS RNA binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Azuma et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ewsr1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ewing sarcoma Alliance Ewing sarcoma 612219
Ewing sarcoma Alliance Neuroepithelioma 612219
Associated With ewsr1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR001876 Zinc finger, RanBP2-type
Family IPR034870 TAF15/EWS/TLS family
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Homologous_superfamily IPR036443 Zinc finger, RanBP2-type superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain TAF15/EWS/TLS family Zinc finger, RanBP2-type Zinc finger, RanBP2-type superfamily
UniProtKB:Q4QRG0 579
UniProtKB:A0A8M3B9G4 311
UniProtKB:A0A8M2BCF1 577
UniProtKB:Q803E3 578
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ewsr1b-201 (1) Ensembl 2,083 nt
mRNA ewsr1b-202 (1) Ensembl 2,441 nt
mRNA ewsr1b-204 (1) Ensembl 897 nt
ncRNA ewsr1b-003 (1) Ensembl 1,207 nt
ncRNA ewsr1b-005 (1) Ensembl 780 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations