Gene
hsd17b12b
- ID
- ZDB-GENE-030131-1346
- Name
- hydroxysteroid (17-beta) dehydrogenase 12b
- Symbol
- hsd17b12b Nomenclature History
- Previous Names
-
- fb68b12
- wu:fb68b12
- zf 3.3 (1)
- zgc:73289
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have estradiol 17-beta-dehydrogenase activity. Predicted to be involved in estrogen biosynthetic process; fatty acid biosynthetic process; and oxidation-reduction process. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NAD(P)-binding domain superfamily | Short-chain dehydrogenase/reductase SDR | VLCFA Elongation and Steroid Dehydrogenase |
|---|---|---|---|---|
|
UniProtKB:A7MCK2
|
311 | |||
|
UniProtKB:Q6QA33
|
311 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hsd17b12b-201
(1)
|
Ensembl | 2,297 nt |
Interactions and Pathways
No data available
Plasmids
No data available