Gene
tnrc6ba
- ID
- ZDB-GENE-030131-13
- Name
- trinucleotide repeat containing adaptor 6Ba
- Symbol
- tnrc6ba Nomenclature History
- Previous Names
-
- tnrc6b
- fa01f05
- fb21h03
- fc23h10
- hm:zeh0114
- im:6968518
- wu:fa01f05 (1)
- wu:fb21h03
- wu:fc23h10
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have nucleic acid binding activity. Predicted to be involved in gene silencing by miRNA and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to localize to P-body and nucleoplasm. Human ortholog(s) of this gene implicated in subserous uterine fibroid and uterine fibroid. Orthologous to human TNRC6B (trinucleotide repeat containing adaptor 6B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Global developmental delay with speech and behavioral abnormalities | 619243 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR019486 | Argonaute hook domain |
| Domain | IPR032226 | TNRC6, PABC binding domain |
| Domain | IPR034925 | TNRC6B, RNA recognition motif |
| Family | IPR052068 | GW182 domain-containing protein |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Argonaute hook domain | GW182 domain-containing protein | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | TNRC6B, RNA recognition motif | TNRC6, PABC binding domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QJF1
|
2006 | ||||||
|
UniProtKB:A0A8M9Q4Q9
|
2000 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnrc6b-201
(1)
|
Ensembl | 7,867 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance