Gene
hp
- ID
- ZDB-GENE-030131-1259
- Name
- haptoglobin
- Symbol
- hp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; artery disease (multiple); gout; hyperglycemia; and obesity. Is expressed in intestine and liver. Orthologous to several human genes including HP (haptoglobin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Family | IPR001314 | Peptidase S1A, chymotrypsin family |
| Family | IPR051487 | Serine/Threonine Proteases with Immune and Developmental Roles |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
Domain Details Per Protein
| Protein | Length | Peptidase S1A, chymotrypsin family | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | Serine proteases, trypsin domain | Serine/Threonine Proteases with Immune and Developmental Roles |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QD27
|
316 |
Interactions and Pathways
No data available
Plasmids
No data available