Gene

azin1b

ID

ZDB-GENE-030121-1

Name

antizyme inhibitor 1b

Symbol

azin1b Nomenclature History

Previous Names

azin1
oazin (1)
wu:fj32d12

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have ornithine decarboxylase activity. Predicted to be involved in putrescine biosynthetic process from ornithine. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7150958 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With azin1b Human Ortholog

No data available

Associated With azin1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR022657	Orn/DAP/Arg decarboxylase 2, conserved site
Domain	IPR022643	Orn/DAP/Arg decarboxylase 2, C-terminal
Domain	IPR022644	Orn/DAP/Arg decarboxylase 2, N-terminal
Family	IPR000183	Ornithine/DAP/Arg decarboxylase
Family	IPR002433	Ornithine decarboxylase
Family	IPR031178	Antizyme inhibitor 1
Homologous_superfamily	IPR009006	Alanine racemase/group IV decarboxylase, C-terminal
Homologous_superfamily	IPR029066	PLP-binding barrel

Domain Details Per Protein

Protein	Length	Alanine racemase/group IV decarboxylase, C-terminal	Antizyme inhibitor 1	Orn/DAP/Arg decarboxylase 2, conserved site	Orn/DAP/Arg decarboxylase 2, C-terminal	Orn/DAP/Arg decarboxylase 2, N-terminal	Ornithine/DAP/Arg decarboxylase	Ornithine decarboxylase	PLP-binding barrel
UniProtKB:Q801V3 InterPro	436

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	azin1b-201 (1) Ensembl	Ensembl	2,808 nt	Select Tool
mRNA	azin1b-202 (1) Ensembl	Ensembl	727 nt	Select Tool
mRNA	azin1b-203 (1) Ensembl	Ensembl	2,446 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations