Gene

lmo1

ID

ZDB-GENE-021115-6

Name

LIM domain only 1

Symbol

lmo1 Nomenclature History

Previous Names

lmo1b
cb524 (1)
etID41074.7 (1)
wu:fb76g02 (1)
zgc:109794

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior axial hypoblast; brain; neural tube; pancreas primordium; and presumptive diencephalon. Orthologous to human LMO1 (LIM domain only 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb524 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lmo1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Leukemia, T-cell acute lymphoblastic	186921

Associated With lmo1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001781	Zinc finger, LIM-type
Family	IPR050945	LMO/RBTN Transcription Factors

Domain Details Per Protein

Protein	Length	LMO/RBTN Transcription Factors	Zinc finger, LIM-type
UniProtKB:A0A8M9Q7H5 InterPro	159
UniProtKB:A0A0R4IIA9 InterPro	175
UniProtKB:B2GQX2 InterPro	155
UniProtKB:A0A8M9Q161 InterPro	179
UniProtKB:Q8JFQ2 InterPro	155