Gene
kat6a
- ID
- ZDB-GENE-021022-3
- Name
- K(lysine) acetyltransferase 6A
- Symbol
- kat6a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits histone acetyltransferase activity. Involved in several processes, including embryonic body morphogenesis; neural crest cell fate specification; and skeletal system morphogenesis. Localizes to nuclear chromatin. Human ortholog(s) of this gene implicated in acute myeloid leukemia and autosomal dominant non-syndromic intellectual disability 32. Is expressed in head. Orthologous to human KAT6A (lysine acetyltransferase 6A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Arboleda-Tham syndrome | Alliance | Arboleda-Tham syndrome | 616268 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR002717 | Histone acetyltransferase domain, MYST-type |
| Domain | IPR005818 | Linker histone H1/H5, domain H15 |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR040706 | MYST, zinc finger domain |
| Domain | IPR048589 | SAM domain-containing protein 1-like, WH domain |
| Family | IPR050603 | MYST family histone acetyltransferases |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR016181 | Acyl-CoA N-acyltransferase |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Acyl-CoA N-acyltransferase | Histone acetyltransferase domain, MYST-type | Linker histone H1/H5, domain H15 | MYST family histone acetyltransferases | MYST, zinc finger domain | SAM domain-containing protein 1-like, WH domain | Winged helix-like DNA-binding domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A2CG09
|
2246 |
Interactions and Pathways
No data available
Plasmids
No data available