Gene

adra2c

ID
ZDB-GENE-021010-3
Name
adrenoceptor alpha 2C
Symbol
adra2c Nomenclature History
Previous Names
  • zgc:194523
  • zgc:194541
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Exhibits alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in congestive heart failure. Is expressed in brain; eye; optic tectum; ovary; and torus lateralis. Orthologous to human ADRA2C (adrenoceptor alpha 2C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adra2c Human Ortholog
No data available
Associated With adra2c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000735 Alpha 2C adrenoceptor
Family IPR002233 Adrenoceptor family
Domain Details Per Protein
Protein Length Adrenoceptor family Alpha 2C adrenoceptor GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:B3DJZ9 432
UniProtKB:Q90WY6 432
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA adra2c-201 (1) Ensembl 1,578 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations