Gene

eef2k

ID

ZDB-GENE-020916-2

Name

eukaryotic elongation factor 2 kinase

Symbol

eef2k Nomenclature History

Previous Names

cb365 (1)
fa04b08
wu:fa04b08
zgc:100973

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have several functions, including ATP binding activity; calmodulin binding activity; and elongation factor-2 kinase activity. Involved in cerebellum vasculature development. Is expressed in epidermis; hatching gland; musculature system; and myotome. Orthologous to human EEF2K (eukaryotic elongation factor 2 kinase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb365 (4 images)
IMAGE:7137793 (1 image)
IMAGE:7147999 (3 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eef2k Human Ortholog

No data available

Associated With eef2k Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004166	Alpha-type protein kinase, alpha-kinase domain
Domain	IPR047588	Eukaryotic elongation factor 2 kinase, alpha-kinase domain
Family	IPR017400	Eukaryotic elongation factor 2 kinase
Family	IPR051852	Alpha-type Protein Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR006597	Sel1-like repeat

Domain Details Per Protein

Protein	Length	Alpha-type Protein Kinase	Alpha-type protein kinase, alpha-kinase domain	Eukaryotic elongation factor 2 kinase	Eukaryotic elongation factor 2 kinase, alpha-kinase domain	Protein kinase-like domain superfamily	Sel1-like repeat	Tetratricopeptide-like helical domain superfamily
UniProtKB:A0A8M2B219 InterPro	743
UniProtKB:Q6DGE0 InterPro	706
UniProtKB:E7F318 InterPro	744
UniProtKB:A0A8M2B2Y1 InterPro	725
UniProtKB:A0A8M2B2E3 InterPro	725