Gene
fabp3
- ID
- ZDB-GENE-020318-2
- Name
- fatty acid binding protein 3, muscle and heart
- Symbol
- fabp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable fatty acid binding activity. Acts upstream of or within chordate embryonic development and heart looping. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including immature eye; muscle; nervous system; pharyngeal arch; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human FABP3 (fatty acid binding protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb889 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| congenital heart disease | WT + MO1-fabp3 | standard conditions | Wang et al., 2013 |
| congenital heart disease | WT + MO2-fabp3 | standard conditions | Wang et al., 2013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein | Lipocalin/cytosolic fatty-acid binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q8UVG7
|
133 |
Interactions and Pathways
No data available
Plasmids