Gene
gria1b
- ID
- ZDB-GENE-020125-2
- Name
- glutamate receptor, ionotropic, AMPA 1b
- Symbol
- gria1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have AMPA glutamate receptor activity and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in ion transport. Predicted to localize to AMPA glutamate receptor complex and dendritic spine. Is expressed in nervous system and otic vesicle. Orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu293 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive intellectual developmental disorder 76 | Alliance | ?Intellectual developmental disorder, autosomal recessive 76 | 619931 |
Intellectual developmental disorder, autosomal dominant 67 | 619927 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
Domain | IPR001638 | Solute-binding protein family 3/N-terminal domain of MltF |
Domain | IPR001828 | Receptor, ligand binding region |
Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
Family | IPR015683 | Ionotropic glutamate receptor |
Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
Protein | Length | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Periplasmic binding protein-like I | Receptor, ligand binding region | Solute-binding protein family 3/N-terminal domain of MltF |
---|---|---|---|---|---|---|---|
UniProtKB:Q71E64
|
917 | ||||||
UniProtKB:F1RE87
|
|||||||
UniProtKB:E7F1V8
|
917 | ||||||
UniProtKB:A0A8M3AU00
|
831 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
aberrant processed transcript |
gria1b-203
(1)
|
Havana | 992 nt | |
mRNA |
gria1b-201
(1)
|
Havana | 3816 nt | |
mRNA |
gria1b-202
(1)
|
Havana | 3515 nt |
Interactions and Pathways
No data available
Plasmids
No data available