Gene
xbp1
- ID
- ZDB-GENE-011210-2
- Name
- X-box binding protein 1
- Symbol
- xbp1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gland development; hatching; and transcription by RNA polymerase II. Predicted to localize to integral component of endoplasmic reticulum membrane and nucleus. Is expressed in several structures, including axial mesoderm; axis; digestive system; ectoderm; and germ ring. Orthologous to human XBP1 (X-box binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 70 figures from 45 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55240 (23 images)
- cb918 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Major affective disorder-7, susceptibility to} | 612371 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily | Endoplasmic Reticulum Stress-Regulated Transcription Factor |
|---|---|---|---|---|
|
UniProtKB:Q90X27
|
263 |
Interactions and Pathways
No data available
Plasmids
No data available