Gene

bco1

ID
ZDB-GENE-010508-1
Name
beta-carotene oxygenase 1
Symbol
bco1 Nomenclature History
Previous Names
  • bcdo1 (1)
  • bcdo
  • bcmo1 (1)
  • bcox (1)
  • bcmo1a
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits beta-carotene 15,15'-monooxygenase activity. Involved in eye photoreceptor cell differentiation and hindbrain development. Is expressed in gut; liver; neural crest; and ovary. Orthologous to human BCO1 (beta-carotene oxygenase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bco1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
carotenemia Alliance ?Hypercarotenemia and vitamin A deficiency, autosomal dominant 115300
Associated With bco1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004294 Carotenoid oxygenase
Domain Details Per Protein
Protein Length Carotenoid oxygenase
UniProtKB:Q7ZTS0 516
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bco1-201 (1) Ensembl 1,790 nt
mRNA bco1-202 (1) Ensembl 2,088 nt
mRNA bco1-203 (1) Ensembl 824 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations