Gene

ucp1

ID
ZDB-GENE-010503-1
Name
uncoupling protein 1
Symbol
ucp1 Nomenclature History
Previous Names
  • ucp4
  • UCPx (1)
  • fb62c08
  • wu:fb62c08
  • zUCPx (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have oxidative phosphorylation uncoupler activity. Involved in cellular response to estrogen stimulus. Predicted to localize to integral component of membrane and mitochondrial membrane. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Is expressed in several structures, including brain; heart; liver; median fin fold; and pleuroperitoneal region. Orthologous to human UCP1 (uncoupling protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ucp1 Human Ortholog
No data available
Associated With ucp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002067 Mitochondrial carrier protein
Family IPR050391 Mitochondrial Metabolite Transporter
Homologous_superfamily IPR023395 Mitochondrial carrier domain superfamily
Repeat IPR018108 Mitochondrial substrate/solute carrier
Domain Details Per Protein
Protein Length Mitochondrial carrier domain superfamily Mitochondrial carrier protein Mitochondrial Metabolite Transporter Mitochondrial substrate/solute carrier
UniProtKB:Q7ZVP4 309
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ucp1-201 (1) Ensembl 2,511 nt
mRNA ucp1-205 (1) Ensembl 938 nt
ncRNA ucp1-002 (1) Ensembl 707 nt
ncRNA ucp1-003 (1) Ensembl 449 nt
ncRNA ucp1-004 (1) Ensembl 526 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations