Gene

vox

ID
ZDB-GENE-010108-1
Name
ventral homeobox
Symbol
vox Nomenclature History
Previous Names
  • vega1
  • zgc:136532
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity and protein homodimerization activity. Involved in dorsal/ventral pattern formation; regulation of endodermal cell fate specification; and regulation of mesodermal cell fate specification. Predicted to localize to nucleus. Is expressed in several structures, including cloacal chamber; embryonic structure; epidermis; hindbrain neural plate; and midbrain neural keel. Orthologous to human VENTX (VENT homeobox).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
46 figures from 35 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vox Human Ortholog
No data available
Associated With vox Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Domain IPR001356 Homeodomain
Family IPR042768 Homeobox protein MNX1/Ceh-12
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Helix-turn-helix motif Homedomain-like superfamily Homeobox protein MNX1/Ceh-12 Homeodomain
UniProtKB:Q9DG33 242
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vox-201 (1) Ensembl 1,623 nt
mRNA vox-202 (1) Ensembl 2,249 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations