Gene

vtg2

ID

ZDB-GENE-001201-2

Name

vitellogenin 2

Symbol

vtg2 Nomenclature History

Previous Names

vg2
si:dkey-4c23.2
zfVtg2 (1)

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Exhibits lipopolysaccharide binding activity and lipoteichoic acid binding activity. Involved in positive regulation of phagocytosis, engulfment and response to estradiol. Is expressed in atrium; intestine; liver; and ovary.

Genome Resources

Note

vtg2-201 and vtg2-202 are described in ZDB-PUB-180609-20. vtg2-201 corresponds to ENSDART00000078328 and vtg2-202 corresponds to ENSDART00000105263

Comparative Information

Expression

All Expression Data

22 figures from 16 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Yilmaz et al., 2023
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vtg2 Human Ortholog

No data available

Associated With vtg2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001747	Vitellogenin, N-terminal
Domain	IPR001846	von Willebrand factor, type D domain
Domain	IPR015255	Vitellinogen, open beta-sheet
Domain	IPR015258	Vitellinogen, beta-sheet shell
Family	IPR050733	Vitellogenin/Apolipophorin
Homologous_superfamily	IPR011030	Lipovitellin-phosvitin complex, superhelical domain
Homologous_superfamily	IPR015816	Vitellinogen, beta-sheet N-terminal
Homologous_superfamily	IPR015817	Vitellinogen, open beta-sheet, subdomain 1
Homologous_superfamily	IPR015819	Lipid transport protein, beta-sheet shell
Homologous_superfamily	IPR037088	Vitellinogen, beta-sheet shell domain superfamily