Gene
fech
- ID
- ZDB-GENE-000928-1
- Name
- ferrochelatase
- Symbol
- fech Nomenclature History
- Previous Names
-
- fch (1)
- dracula
- drc
- frx
- zgc:109851
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Exhibits ferrochelatase activity. Involved in erythrocyte maturation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in cutaneous porphyria and erythropoietic protoporphyria. Is expressed in blood; intermediate cell mass of mesoderm; posterior lateral plate mesoderm; and ventral mesoderm. Orthologous to human FECH (ferrochelatase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109851 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| erythropoietic protoporphyria | Alliance | Protoporphyria, erythropoietic, 1 | 177000 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ferrochelatase | Ferrochelatase, active site | Ferrochelatase, C-terminal | Ferrochelatase, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PIE9
|
409 | ||||
|
UniProtKB:Q9DFU9
|
409 |
Interactions and Pathways
No data available
Plasmids
No data available