Gene

tradd

ID

ZDB-GENE-000511-5

Name

tnfrsf1a-associated via death domain

Symbol

tradd Nomenclature History

Previous Names

hm:zehn0873
wu:fc59e02 (1)
zehn0873
zgc:103556

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have molecular adaptor activity. Involved in positive regulation of apoptotic process. Predicted to localize to cytoplasm; cytoskeleton; and nucleus. Orthologous to human TRADD (TNFRSF1A associated via death domain).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhang et al., 2021

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tradd Human Ortholog

No data available

Associated With tradd Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR009095	TRADD, N-terminal
Family	IPR035712	TRADD
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR036729	TRADD, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Death domain	Death-like domain superfamily	TRADD	TRADD, N-terminal	TRADD, N-terminal domain superfamily
UniProtKB:B2GNQ4 InterPro	293
UniProtKB:Q9I9N5 InterPro	293

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tradd-201 (1) Ensembl	Ensembl		1,302 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations