Gene
ppardb
- ID
- ZDB-GENE-000112-47
- Name
- peroxisome proliferator-activated receptor delta b
- Symbol
- ppardb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II repressing transcription factor binding activity; and nuclear receptor transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of cholesterol storage; positive regulation of fatty acid metabolic process; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in brain; intestine; liver; and ovary. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- af342938 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003074 | Peroxisome proliferator-activated receptor |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Peroxisome proliferator-activated receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A9C4A5
|
517 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppardb-201
(1)
|
Ensembl | 4,212 nt | ||
| mRNA |
ppardb-202
(1)
|
Ensembl | 2,576 nt | ||
| mRNA |
ppardb-203
(1)
|
Ensembl | 1,110 nt | ||
| mRNA |
ppardb-204
(1)
|
Ensembl | 909 nt | ||
| mRNA |
ppardb-205
(1)
|
Ensembl | 1,685 nt |
Interactions and Pathways
No data available
Plasmids
No data available