FISH

WT + CRISPR1-mecp2

ID: ZDB-FISH-151014-40
Name: WT + CRISPR1-mecp2
Genotype: WT
Targeting Reagent: CRISPR1-mecp2

Human Disease modelled by WT + CRISPR1-mecp2

Disease	Conditions	Citation
Rett syndrome	standard conditions	Gao et al., 2015

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Gene Expression

RNA Expression

Protein Expression

No data available

Reporter Gene Expression

No data available

Phenotype

Phenotype	Conditions	Figures
brain has extra parts of type neuronal stem cell, abnormal	standard conditions	Fig. 7 from Gao et al., 2015
brain has extra parts of type astrocyte, abnormal	standard conditions	Fig. 7 from Gao et al., 2015
brain has fewer parts of type neuron, abnormal	standard conditions	Fig. 7 from Gao et al., 2015
brain astrocyte differentiation increased occurrence, abnormal	standard conditions	Fig. 7 from Gao et al., 2015
brain neural precursor cell proliferation increased occurrence, abnormal	standard conditions	Fig. 7 from Gao et al., 2015
brain neuron differentiation decreased occurrence, abnormal	standard conditions	Fig. 7 from Gao et al., 2015

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Citations

Include unpublished citations

Gao, H., Bu, Y., Wu, Q., Wang, X., Chang, N., Lei, L., Chen, S., Liu, D., Zhu, X., Hu, K., Xiong, J.W. (2015) Mecp2 regulates neural cell differentiation by suppressing the Id1-Her2/Hes5 axis in zebrafish. Journal of Cell Science. 128(12):2340-50

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