CRISPR

CRISPR1-clcn7

ID
ZDB-CRISPR-241031-6
Name
CRISPR1-clcn7
Previous Names
None
Target
Sequence
5' - GGAGCGGTGTTCTCTCTCCGCGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The first two "G"s were added.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
st167 clcn7
Expression
Gene expression in Wild Types + CRISPR1-clcn7
No data available
Phenotype
Phenotype resulting from CRISPR1-clcn7
No data available
Phenotype of all Fish created by or utilizing CRISPR1-clcn7
Phenotype Fish Conditions Figures
microglial cell decreased accumulation microglial cell neutral red, abnormal clcn7st167/st167 (AB/TL) chemical treatment by environment: neutral red Fig. 1. with image from Iyer et al., 2024
microglial cell phagocytosis, engulfment increased process quality, abnormal clcn7st167/st167; gl22Tg (AB/TL) chemical treatment by injection: amyloid-beta polypeptide 42 Fig. 4. with image from Iyer et al., 2024
macrophage phagocytosis, engulfment increased process quality, abnormal clcn7st167/st167; gl22Tg (AB/TL) bacterial treatment by injection: Escherichia coli K-12 Fig. 4. with image from Iyer et al., 2024
microglial cell apoptotic process increased process quality, abnormal clcn7st167/st167; gl22Tg (AB/TL) standard conditions Fig. 3. with image from Iyer et al., 2024
Citations
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