CRISPR

CRISPR2-pparg

ID

ZDB-CRISPR-230822-1

Name

CRISPR2-pparg

Previous Names

None

Target

pparg (1)

Sequence

5' - GGACACACGAGCCCATCTAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3729	pparg

Expression

Gene expression in Wild Types + CRISPR2-pparg

No data available

Phenotype

Phenotype resulting from CRISPR2-pparg

No data available

Phenotype of all Fish created by or utilizing CRISPR2-pparg

Phenotype	Fish	Conditions	Figures
liver lipid droplet amount, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022
liver vacuole decreased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 2 from Zhao et al., 2022
liver vacuole amount, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022
whole organism weight, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022
liver triglyceride decreased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 2 from Zhao et al., 2022
liver pparg expression decreased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
liver phosphatidylcholine increased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
liver cholesterol amount, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022
male organism hepatocyte congested, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
liver monoacylglycerol increased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
liver weight, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022
liver lipid droplet decreased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 2 from Zhao et al., 2022
liver lysophosphatidylcholine increased amount, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
male organism hepatocyte transparent, abnormal	pparg^{zf3729/zf3729} (AB)	standard conditions	Fig. 1 from Zhao et al., 2022
liver triglyceride amount, ameliorated	pparg^{zf3729/zf3729} (AB)	high fat	Fig. 2 from Zhao et al., 2022

Citations