CRISPR

CRISPR1-slc38a9

ID
ZDB-CRISPR-221206-7
Name
CRISPR1-slc38a9
Previous Names
None
Target
Sequence
5' - AGGACAGTAAACCGTTACTG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "GGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ouc101 slc38a9
ouc102 slc38a9
Expression
Gene expression in Wild Types + CRISPR1-slc38a9
No data available
Phenotype
Phenotype resulting from CRISPR1-slc38a9
No data available
Phenotype of all Fish created by or utilizing CRISPR1-slc38a9
Phenotype Fish Conditions Figures
whole organism dead, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with image from Wu et al., 2022
pericardium edematous, exacerbated slc38a9ouc101/ouc101 hypoxia Figure 7 with image from Wu et al., 2022
whole organism hhip expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism slc38a9 expression decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with image from Wu et al., 2022
eye decreased size, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with imageFigure 7 with image from Wu et al., 2022
whole organism apoptotic process increased process quality, abnormal slc38a9ouc101/ouc101 standard conditions Figure 4 with image from Wu et al., 2022
whole organism cnot1 expression decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism lactate increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 6 with image from Wu et al., 2022
whole organism gpt2 expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism kars1 expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism igfbp1a expression increased amount, abnormal slc38a9ouc101/ouc101 hypoxia Figure 7 with image from Wu et al., 2022
whole organism viability, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with image from Wu et al., 2022
whole organism alanine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism leucine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism pyruvate decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 6 with image from Wu et al., 2022
whole organism histidine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism semi-viable, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with image from Wu et al., 2022
whole organism serine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism methionine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism tyrosine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism glucose decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 6 with image from Wu et al., 2022
whole organism vegfaa expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 7 with image from Wu et al., 2022
whole organism D-glucose 6-phosphate decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 6 with image from Wu et al., 2022
whole organism thrb expression decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism length, exacerbated slc38a9ouc101/ouc101 hypoxia Figure 7 with image from Wu et al., 2022
whole organism decreased length, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with imageFigure 7 with image from Wu et al., 2022
whole organism ddit4 expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 7 with image from Wu et al., 2022
whole organism glycine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism got2b expression decreased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism lysine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism valine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism ddit4 expression amount, ameliorated slc38a9ouc101/ouc101 hypoxia Figure 7 with image from Wu et al., 2022
pericardium edematous, abnormal slc38a9ouc101/ouc101 standard conditions Figure 2 with imageFigure 7 with image from Wu et al., 2022
whole organism threonine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism igfbp1a expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with imageFigure 7 with image from Wu et al., 2022
whole organism eif2s1b expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism isoleucine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
eye size, exacerbated slc38a9ouc101/ouc101 hypoxia Figure 7 with image from Wu et al., 2022
heart contraction decreased rate, abnormal slc38a9ouc101/ouc101 standard conditions Figure 3 with image from Wu et al., 2022
whole organism hmox1a expression increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 7 with image from Wu et al., 2022
whole organism phenylalanine increased amount, abnormal slc38a9ouc101/ouc101 standard conditions Figure 5 with image from Wu et al., 2022
whole organism slc38a9 expression decreased amount, abnormal slc38a9ouc102/ouc102 standard conditions Figure 2 with image from Wu et al., 2022
Citations