CRISPR

CRISPR1-pparg

ID

ZDB-CRISPR-211116-4

Name

CRISPR1-pparg

Previous Names

None

Target

pparg (1)

Sequence

5' - GGGCTTCGGCCTGAGCGCTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ecn6	pparg

Expression

Gene expression in Wild Types + CRISPR1-pparg

No data available

Phenotype

Phenotype resulting from CRISPR1-pparg

No data available

Phenotype of all Fish created by or utilizing CRISPR1-pparg

Phenotype	Fish	Conditions	Figures
female organism pleuroperitoneal region pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
male organism liver Ab4-pparg labeling decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
male organism decreased life span, abnormal	pparg^ecn6/ecn6 (AB)	chemical treatment by environment: ammonium chloride	Fig. 2 from Wang et al., 2022
liver triglyceride decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
male organism pleuroperitoneal region pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism liver composition, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
female organism nfe2l2a expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
female organism decreased life span, abnormal	pparg^ecn6/ecn6 (AB)	chemical treatment by environment: ammonium chloride	Fig. 2 from Wang et al., 2022
female organism aerobic respiration decreased rate, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
female organism lipase activity increased occurrence, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
male organism muscle pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
male organism liver pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
visceral fat decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
male organism pleuroperitoneal region Ab4-pparg labeling decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism triglyceride decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
female organism superoxide dismutase activity decreased occurrence, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
female organism visceral fat decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism decreased life span, abnormal	pparg^ecn6/ecn6 (AB)	heat exposure	Fig. 2 from Wang et al., 2022
female organism cat expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
male organism intestine pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism sod1 expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
male organism testis pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism liver Ab4-pparg labeling decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism decreased life span, abnormal	pparg^ecn6/ecn6 (AB)	cold exposure	Fig. 2 from Wang et al., 2022
female organism fatty acid increased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
female organism ovary pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism muscle pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism cholesterol decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
female organism intestine pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism liver pparg expression decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022
female organism reactive oxygen species increased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 3 from Wang et al., 2022
whole organism decreased weight, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 2 from Wang et al., 2022
female organism pleuroperitoneal region Ab4-pparg labeling decreased amount, abnormal	pparg^ecn6/ecn6 (AB)	standard conditions	Fig. 1 from Wang et al., 2022

Citations