CRISPR

CRISPR2-klf2b

ID

ZDB-CRISPR-210108-3

Name

CRISPR2-klf2b

Previous Names

None

Target

klf2b (1)

Sequence

5' - GGATGCAACCCAGCATGCAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
fdu032	klf2b
fdu033	klf2b

Expression

Gene expression in Wild Types + CRISPR2-klf2b

No data available

Phenotype

Phenotype resulting from CRISPR2-klf2b

No data available

Phenotype of all Fish created by or utilizing CRISPR2-klf2b

Phenotype	Fish	Conditions	Figures
whole organism klf2b expression decreased amount, abnormal	klf2b^{fdu033/fdu033}	standard conditions	Figure 2 from Li et al., 2020
whole organism klf2a expression increased amount, abnormal	klf2b^{fdu033/fdu033}	standard conditions	Figure 2 from Li et al., 2020
heart klf2b expression decreased amount, abnormal	klf2b^{fdu033/fdu033}	control	Figure 2 from Li et al., 2020
heart klf2a expression increased amount, abnormal	klf2b^{fdu033/fdu033}	control	Figure 2 from Li et al., 2020
heart notch1b expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	chemical treatment by environment: metronidazole	Figure 2 from Li et al., 2020
heart klf2b expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	control	Figure 2 from Li et al., 2020
heart notch1b expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	control	Figure 2 from Li et al., 2020
whole organism klf2a expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	standard conditions	Figure 2 from Li et al., 2020
whole organism klf2b expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	standard conditions	Figure 2 from Li et al., 2020
heart klf2a expression amount, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}	control	Figure 2 from Li et al., 2020
heart Notch signaling pathway occurrence, ameliorated	klf2b^{fdu033/fdu033}; mw43Tg; s957Tg	chemical treatment by environment: metronidazole	Figure 2 from Li et al., 2020
heart cardiac muscle tissue regeneration decreased occurrence, abnormal	klf2b^{fdu033/fdu033}; s957Tg	chemical treatment by environment: metronidazole	Figure 2 from Li et al., 2020
heart Notch signaling pathway occurrence, ameliorated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}; mw43Tg; s957Tg	chemical treatment by environment: metronidazole	Figure 2 from Li et al., 2020
heart cardiac muscle tissue regeneration decreased occurrence, exacerbated	klf2a^{fdu031/fdu031}; klf2b^{fdu033/fdu033}; s957Tg	chemical treatment by environment: metronidazole	Figure 2 from Li et al., 2020

Citations