CRISPR

CRISPR2-arnt

ID

ZDB-CRISPR-201102-3

Name

CRISPR2-arnt

Previous Names

None

Target

arnt (1)

Sequence

5' - CTGGAAACACCAGCACCGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sh544	arnt

Expression

Gene expression in Wild Types + CRISPR2-arnt

No data available

Phenotype

Phenotype resulting from CRISPR2-arnt

No data available

Phenotype of all Fish created by or utilizing CRISPR2-arnt

Phenotype	Fish	Conditions	Figures
whole organism cortisol increased amount, abnormal	arnt^sh544/sh544; sh144Tg	standard conditions	Fig. 2 from Marchi et al., 2020
adenohypophysis pomca expression decreased amount, abnormal	arnt^sh544/sh544; sh144Tg	standard conditions	Fig. 2 from Marchi et al., 2020
adenohypophysis pomca expression decreased amount, abnormal	arnt^sh544/sh544; sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 2 from Marchi et al., 2020
whole organism fkbp5 expression decreased amount, abnormal	arnt^sh544/sh544; sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 2 from Marchi et al., 2020
whole organism fkbp5 expression amount, ameliorated	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism vegfab expression increased amount, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism egln3 expression increased amount, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism hypoxia-inducible factor-1alpha signaling pathway decreased efficacy, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	standard conditions	Fig. 1 from Marchi et al., 2020
whole organism fkbp5 expression decreased amount, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism vegfab expression increased amount, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism egln3 expression increased amount, abnormal	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism hypoxia-inducible factor-1alpha signaling pathway decreased efficacy, exacerbated	vhl^{hu2117/hu2117}; arnt^sh544/sh544; sh144Tg/sh144Tg + CRISPR1-arnt2 + CRISPR2-arnt2 + CRISPR3-arnt2 + CRISPR4-arnt2	standard conditions	Fig. 1 from Marchi et al., 2020

Citations