CRISPR

CRISPR1-irx1b

ID

ZDB-CRISPR-200204-30

Name

CRISPR1-irx1b

Previous Names

None

Target

irx1b (1)

Sequence

5' - AGAGCGCTACCAGAGAAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3176	irx1b

Expression

Gene expression in Wild Types + CRISPR1-irx1b

No data available

Phenotype

Phenotype resulting from CRISPR1-irx1b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-irx1b

Phenotype	Fish	Conditions	Figures
whole organism sterile, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 1 from Jung et al., 2019
whole organism ccnd1 expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
whole organism cdkn1a expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
whole organism ccne1 expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
intestine carcinoma present, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 3, Fig. 4 from Jung et al., 2019
whole organism cdkn2a/b expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
whole organism cdkn2d expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
whole organism carcinoma proliferative, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 4 from Jung et al., 2019
whole organism morphology, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 1 from Jung et al., 2019
testis carcinoma present, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 3 from Jung et al., 2019
pancreas carcinoma present, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 4 from Jung et al., 2019
whole organism carcinoma hyperplastic, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 3 from Jung et al., 2019
whole organism il6 expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
kidney carcinoma present, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 3 from Jung et al., 2019
intrahepatic bile duct carcinoma present, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 4 from Jung et al., 2019
ovary cystic, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 3 from Jung et al., 2019
whole organism cdkn2c expression increased amount, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 5 from Jung et al., 2019
whole organism decreased life span, abnormal	irx1a^{zf3177/zf3177}; irx1b^{zf3176/zf3176} (AB)	standard conditions	Fig. 1 from Jung et al., 2019

Citations