CRISPR

CRISPR1-osbpl2b

ID

ZDB-CRISPR-200122-28

Name

CRISPR1-osbpl2b

Previous Names

None

Target

osbpl2b (1)

Sequence

5' - GAGCTTTCTACAGAGACTTA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3155	osbpl2b

Expression

Gene expression in Wild Types + CRISPR1-osbpl2b

No data available

Phenotype

Phenotype resulting from CRISPR1-osbpl2b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-osbpl2b

Phenotype	Fish	Conditions	Figures
inner ear cholesterol increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2 from Wang et al., 2019
inner ear hmgcs1 expression increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2, Fig. S3 from Wang et al., 2019
inner ear reactive oxygen species increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 5 from Wang et al., 2019
inner ear hmgcra expression increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. S3 from Wang et al., 2019
inner ear Ab2-hmgcr labeling increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2 from Wang et al., 2019
inner ear itgb7 expression decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 4 from Shi et al., 2019
inner ear cd8a expression decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 4 from Shi et al., 2019
inner ear Ab3-prkaa labeling decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2 from Wang et al., 2019
inner ear srebf2 expression increased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2, Fig. S3 from Wang et al., 2019
inner ear uba3 expression decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 4 from Shi et al., 2019
inner ear col6a1 expression decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 4 from Shi et al., 2019
inner ear pdgfbb expression decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 4 from Shi et al., 2019
inner ear Ab1-acaca labeling decreased amount, abnormal	osbpl2b^{zf3155/zf3155}	standard conditions	Fig. 2 from Wang et al., 2019

Citations