CRISPR

CRISPR1-cxcr3.3

ID
ZDB-CRISPR-190830-2
Name
CRISPR1-cxcr3.3
Previous Names
None
Target
Sequence
5' - GACTGGTTCTGGCAGTATTG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "TGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ibl50 cxcr3.3
Expression
Gene expression in Wild Types + CRISPR1-cxcr3.3
No data available
Phenotype
Phenotype resulting from CRISPR1-cxcr3.3
No data available
Phenotype of all Fish created by or utilizing CRISPR1-cxcr3.3
Phenotype Fish Conditions Figures
whole organism cxcl11.1 expression increased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) amputation: caudal fin Fig. S4 from Sommer et al., 2019
whole organism cxcr3.3 expression decreased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) control Figure 2 with image from Sommer et al., 2019
defense response to bacterium decreased efficacy, abnormal cxcr3.3ibl50/ibl50 (AB/TL) bacterial treatment by injection: Mycobacterium marinum M Figure 3 with image from Sommer et al., 2019
whole organism cxcr3.2 expression increased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) bacterial treatment by injection: Mycobacterium marinum M Figure 3 with image from Sommer et al., 2019
whole organism cxcl11.1 expression increased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) bacterial treatment by injection: Mycobacterium marinum M Figure 3 with image from Sommer et al., 2019
whole organism il1b expression increased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) amputation: caudal fin Fig. S4 from Sommer et al., 2019
whole organism tnfa expression increased amount, abnormal cxcr3.3ibl50/ibl50 (AB/TL) amputation: caudal fin Fig. S4 from Sommer et al., 2019
macrophage chemotaxis increased occurrence, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) amputation: caudal fin Figure 5 with image from Sommer et al., 2019
macrophage activation involved in immune response increased occurrence, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) bacterial treatment by injection: Mycobacterium marinum M Figure 5 with image from Sommer et al., 2019
caudal fin macrophage increased amount, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) control Figure 2 with image from Sommer et al., 2019
macrophage chemotaxis increased occurrence, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) bacterial treatment by injection: Mycobacterium marinum M Figure 5 with image from Sommer et al., 2019
macrophage increased speed, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) amputation: caudal fin Figure 7 with image from Sommer et al., 2019
macrophage increased speed, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) control Figure 7 with image from Sommer et al., 2019
whole organism macrophage increased amount, abnormal cxcr3.3ibl50/ibl50; ump2Tg (AB/TL) control Figure 2 with image from Sommer et al., 2019
Citations
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