CRISPR

CRISPR6-tnnt2a

ID
ZDB-CRISPR-190522-3
Name
CRISPR6-tnnt2a
Previous Names
None
Target
Sequence
5' - GGGAGCGACAGAAGCGTT - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
fdu108 tnnt2a
Expression
Gene expression in Wild Types + CRISPR6-tnnt2a
No data available
Phenotype
Phenotype resulting from CRISPR6-tnnt2a
No data available
Phenotype of all Fish created by or utilizing CRISPR6-tnnt2a
Phenotype Fish Conditions Figures
heart muscle contraction arrested, abnormal tnnt2afdu108/fdu108; fdu107Tg standard conditions Fig. 1. with image from Liu et al., 2019
pericardium edematous, abnormal tnnt2afdu108/fdu108; twu34Tg standard conditions Fig. 1. with image from Liu et al., 2019
heart contraction arrested, abnormal tnnt2afdu108/fdu108; twu34Tg standard conditions Fig. 1. with image from Liu et al., 2019
atrium distended, abnormal tnnt2afdu108/fdu108; twu34Tg standard conditions Fig. 1. with image from Liu et al., 2019
cardiac ventricle distended, abnormal tnnt2afdu108/fdu108; twu34Tg standard conditions Fig. 1. with image from Liu et al., 2019
heart tnnt2a expression amount, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with imageFig. 3. with image from Liu et al., 2019
heart myl7 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
blood circulation decreased rate, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with image from Liu et al., 2019
blood circulation decreased rate, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
heart bmp2b expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart tpm4a expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
pericardium edematous, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with image from Liu et al., 2019
heart tnni1b expression amount, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart tbx20 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart contraction arrested, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with imageFig. 4. with image from Liu et al., 2019
atrium distended, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with image from Liu et al., 2019
heart tnnc1a expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
cardiac ventricle distended, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
atrium distended, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
heart contraction rate, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
heart contraction arrested, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
heart actc1a expression amount, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart myl7 expression amount, ameliorated tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
bulbus arteriosus decreased diameter, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 4. with image from Liu et al., 2019
heart gata5 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart tnnt2a expression absent, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with imageFig. 3. with image from Liu et al., 2019
bulbus arteriosus decreased contractility, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 4. with image from Liu et al., 2019
cardiac ventricle distended, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 2. with image from Liu et al., 2019
heart tpm4a expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
pericardium edematous, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 2. with image from Liu et al., 2019
heart has2 expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart contraction decreased rate, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 4. with image from Liu et al., 2019
heart tbx2b expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart actc1a expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart gata5 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart gata4 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart tnni1b expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg standard conditions Fig. 3. with image from Liu et al., 2019
heart tnnc1a expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart gata4 expression increased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart bmp2b expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
heart tbx2b expression decreased amount, abnormal tnnt2afdu108/fdu108; fdu106Tg chemical treatment by environment: doxycycline Fig. 3. with image from Liu et al., 2019
Citations