CRISPR

CRISPR1-lars1b

ID

ZDB-CRISPR-190212-5

Name

CRISPR1-lars1b

Previous Names

CRISPR1-larsb

Target

lars1b (1)

Sequence

5' - GGAGGGGTCCTCAGTGGACA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
cq68	lars1b

Expression

Gene expression in Wild Types + CRISPR1-lars1b

No data available

Phenotype

Phenotype resulting from CRISPR1-lars1b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-lars1b

Phenotype	Fish	Conditions	Figures
eye decreased size, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2 from Wang et al., 2018
liver fabp10a expression decreased amount, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2, Fig. 4 from Wang et al., 2018
liver cp expression decreased amount, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2 from Wang et al., 2018
swim bladder absent, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2 from Wang et al., 2018
heart edematous, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2 from Wang et al., 2018
liver fabp10a expression amount, ameliorated	lars1b^cq68/cq68	chemical treatment by environment: sirolimus	Fig. 4 from Wang et al., 2018
head decreased size, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2 from Wang et al., 2018
liver decreased size, abnormal	lars1b^cq68/cq68	standard conditions	Fig. 2, Fig. 4 from Wang et al., 2018
liver size, ameliorated	lars1b^cq68/cq68	chemical treatment by environment: sirolimus	Fig. 4 from Wang et al., 2018
hepatocyte TORC1 signaling increased occurrence, abnormal	lars1b^cq68/cq68; gz15Tg	standard conditions	Fig. 4 from Wang et al., 2018
liver DNA damage response increased occurrence, abnormal	lars1b^cq68/cq68; gz15Tg	standard conditions	Fig. 3 from Wang et al., 2018
liver fabp10a expression amount, ameliorated	lars1b^cq68/cq68 + MO1-mtor	standard conditions	Fig. 4 from Wang et al., 2018
liver size, ameliorated	lars1b^cq68/cq68 + MO1-mtor	standard conditions	Fig. 4 from Wang et al., 2018
hepatocyte cell population proliferation decreased process quality, abnormal	lars1b^cq68/cq68; cq1Tg	standard conditions	Fig. 3 from Wang et al., 2018

Citations