CRISPR

CRISPR1-slc18a2

ID

ZDB-CRISPR-160415-1

Name

CRISPR1-slc18a2

Previous Names

None

Target

slc18a2 (1)

Sequence

5' - GGACGACGAGGCTGCTCAGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sus100	slc18a2
sus101	slc18a2
zf3752	slc18a2

Expression

Gene expression in Wild Types + CRISPR1-slc18a2

No data available

Phenotype

Phenotype resulting from CRISPR1-slc18a2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-slc18a2

Phenotype	Fish	Conditions	Figures
heart heart contraction increased rate of continuous process, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 1 from Baronio et al., 2021
brain ab1-serotonin labeling decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 6 from Baronio et al., 2021
whole organism serotonin decreased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 6 from Baronio et al., 2021
brain hdc expression increased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 3 from Baronio et al., 2021
whole organism histamine decreased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 3 from Baronio et al., 2021
whole organism slc18a2 expression decreased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 1 from Baronio et al., 2021
hindbrain pax2a expression decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 7 from Baronio et al., 2021
hypothalamus posterior region th2 expression increased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 4 from Baronio et al., 2021
whole organism th2 expression increased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 4 from Baronio et al., 2021
startle response increased process quality, abnormal	slc18a2^{zf3752/zf3752}	altered light dark cycle	Fig. 2 from Baronio et al., 2021
midbrain pax2a expression decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 7 from Baronio et al., 2021
swimming behavior decreased process quality, abnormal	slc18a2^{zf3752/zf3752}	altered light dark cycle	Fig. 2 from Baronio et al., 2021
brain slc18a2 expression decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 1 from Baronio et al., 2021
whole organism manf expression increased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 7 from Baronio et al., 2021
whole organism (5-hydroxyindol-3-yl)acetic acid increased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 6 from Baronio et al., 2021
whole organism th expression increased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 4 from Baronio et al., 2021
whole organism notch1a expression decreased amount, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 7 from Baronio et al., 2021
hypothalamus ab1-histamine labeling decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 3 from Baronio et al., 2021
brain notch1a expression decreased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 7 from Baronio et al., 2021
hypothalamus tph1a expression increased distribution, abnormal	slc18a2^{zf3752/zf3752}	standard conditions	Fig. 6 from Baronio et al., 2021
brain serotonin decreased amount, abnormal	slc18a2^sus100/+	standard conditions	Fig. 4 from Wang et al., 2016
brain (5-hydroxyindol-3-yl)acetic acid increased amount, abnormal	slc18a2^sus100/+	standard conditions	Fig. 4 from Wang et al., 2016
brain noradrenaline decreased amount, abnormal	slc18a2^sus100/+	standard conditions	Fig. 4 from Wang et al., 2016
brain dopamine decreased amount, abnormal	slc18a2^sus100/+	standard conditions	Fig. 4 from Wang et al., 2016
locomotory exploration behavior process quality, abnormal	slc18a2^sus100/+	standard conditions	Fig. 3 from Wang et al., 2016
swimming behavior process quality, abnormal	slc18a2^sus100/+	standard conditions	Fig. 2 from Wang et al., 2016
locomotory exploration behavior process quality, abnormal	slc18a2^sus101/+	standard conditions	Fig. 3 from Wang et al., 2016
swimming behavior process quality, abnormal	slc18a2^sus101/+	standard conditions	Fig. 2 from Wang et al., 2016

Citations