CRISPR
CRISPR2-tjp1b
- ID
- ZDB-CRISPR-150731-13
- Name
- CRISPR2-tjp1b
- Previous Names
-
- Z000461 (1)
- Target
- Sequence
-
5' - GTGGGCTTGAGGCTCGCTGG - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
- None
- Genome Resources
Target Location
Constructs
No data available
Genomic Features
Expression
Gene expression in Wild Types + CRISPR2-tjp1b
No data available
Phenotype
Phenotype resulting from CRISPR2-tjp1b
No data available
Phenotype of all Fish created by or utilizing CRISPR2-tjp1b
| Phenotype | Fish | Conditions | Figures |
|---|---|---|---|
| epiboly increased duration, abnormal | tjp1be122Tg/e122Tg; tjp3e123Tg/e123Tg | standard conditions |
Fig. 2 
from Schwayer et al., 2019 |
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Citations
- Schwayer, C., Shamipour, S., Pranjic-Ferscha, K., Schauer, A., Balda, M., Tada, M., Matter, K., Heisenberg, C.P. (2019) Mechanosensation of Tight Junctions Depends on ZO-1 Phase Separation and Flow. Cell. 179:937-952.e18
- Marsh, A.J., Michel, J.C., Adke, A.P., Heckman, E.L., Miller, A.C. (2017) Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses. Current biology : CB. 27:3561-3567.e4
- Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2015) Rapid reverse genetic screening using CRISPR in zebrafish. Nature Methods. 12(6):535-40
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