| Name: | whole organism |
|---|---|
| Synonyms: | multi-cellular organism |
| Definition: | Anatomical structure that is an individual member of Danio rerio. |
| Ontology: | Anatomy Ontology [ZFA:0001094] |
| Name: | increased sensitivity toward |
|---|---|
| Synonyms: | high sensitivity toward, increased sensitivity |
| Definition: | A sensitivity toward an external stimulus which is higher than normal/average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001549] |
| Name: | thapsigargin |
|---|---|
| Synonyms: | (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate, octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester, Tg, Thapsigargin, thapsigargine |
| Definition: | An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. |
| Ontology: | ChEBI [CHEBI:9516] ( EBI ) |