Term Name: | ito cell |
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Synonyms: | hepatic stellate cell, perisinusoidal cell |
Definition: | A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype. |
Appears at: | Unknown |
Evident until: | Adult (90d-730d, breeding adult) |
Ontology: | Anatomy Ontology [ZFA:0009279] |
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