Term Name: | Nkx-2.5 complex |
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Synonyms: | Nkx-2.5 homodimer complex, NKX.2-5 homodimer complex, NKX2.5 complex, NKX2E homodimer complex |
Definition: | A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. |
Ontology: | GO: Cellular Component [GO:1990664] QuickGO AmiGO |