Term Name: | ATF4-CREB1 transcription factor complex |
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Synonyms: | |
Definition: | Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway. |
Ontology: | GO: Cellular Component [GO:1990589] QuickGO AmiGO |