Term Name: | separase-securin complex |
---|---|
Synonyms: | Cut1-2 complex |
Definition: | A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC). |
Ontology: | GO: Cellular Component [GO:1990520] QuickGO AmiGO |