Term Name: | PTEN phosphatase complex |
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Synonyms: | phosphatase and tensin homolog, phosphatase and tensin homolog deleted on chromosome ten homodimer, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer |
Definition: | A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function. |
Ontology: | GO: Cellular Component [GO:1990455] QuickGO AmiGO |