Term Name: intrinsic apoptotic signaling pathway in response to hypoxia
Synonyms:
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.
Ontology: GO: Biological Process [GO:1990144]    QuickGO    AmiGO

Relationships
is part of: cellular response to hypoxia
is a type of: intrinsic apoptotic signaling pathway
negatively regulated by: negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
regulated by: regulation of hypoxia-induced intrinsic apoptotic signaling pathway