Term Name: RQC-trigger complex
Synonyms: activating signal cointegrator 1 complex, RQT complex
Definition: A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.
Ontology: GO: Cellular Component [GO:0180022]    QuickGO    AmiGO

Relationships
is a type of: protein-containing complex