Term Name: | oxoadipate dehydrogenase complex |
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Synonyms: | OADHC |
Definition: | A multi-enzyme complex that catalyzes the oxidative decarboxylation of 2-oxoadipate to glutaryl-CoA, thereby acting in the final step of lysine and tryptophan catabolism in mitochondria. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: 2-oxoadipate dehydrogenase (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). |
Ontology: | GO: Cellular Component [GO:0160167] QuickGO AmiGO |