Term Name: | hypoxia-inducible factor-proline dioxygenase activity |
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Synonyms: | HIF hydroxylase, HIF prolyl hydroxylase |
Definition: | Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]. |
Ontology: | GO: Molecular Function [GO:0160082] QuickGO AmiGO |