Term Name: | amylin receptor complex 3 |
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Synonyms: | AMY3 complex |
Definition: | A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways. |
Ontology: | GO: Cellular Component [GO:0150058] QuickGO AmiGO |