Term Name: | inflammasome-mediated signaling pathway |
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Synonyms: | inflammasome-mediated signal transduction |
Definition: | An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis. |
Ontology: | GO: Biological Process [GO:0141084] QuickGO AmiGO |