Term Name: | retrotransposon silencing by siRNA-directed DNA methylation |
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Synonyms: | retrostransposon silencing by RdDM, retrotransposon silencing by RNA-directed DNA methylation |
Definition: | A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. |
Ontology: | GO: Biological Process [GO:0141010] QuickGO AmiGO |