Term Name: | PAR polarity complex |
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Synonyms: | apical polarity complex, BEM1-CDC24-CLA4 complex, Cdc42p GEF-PAK complex, PAR3-PAR6-atypical PKC, PAR3/PAR6/aPKC, PAR6-PAR3-aPKC complex |
Definition: | A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. |
Ontology: | GO: Cellular Component [GO:0120157] QuickGO AmiGO |